RR: CBD is the primary cannabinoid found in hemp (cannabis fiber) and the second (and sometimes first) cannabinoid found in marijuana (medicinal cannabis). It’s usually found in certified cannabis strains at 1% to 4%, but in Colorado, CBD can be as high as 26%. Think of it as cannabis with the cannabinoid ratio inverted.
SP: CBD is a cannabinoid or plant compound known as cannabidiol, found in the Cannabis Sativa L plant. Also known as Hemp, Marijuana, Weed, Ganja and a few other titles. CBD is just one of hundreds of thousands of cannabinoids that may be found in these plants.
AU: Cannabidiol (CBD), a phytocannabinoid, is the most abundant non-psychoactive component of the cannabis and hemp plant. CBD has been reported to play a protective role in a variety of diseases and to have apoptotic, anti-inflammatory and antioxidant effects.First isolated from cannabis by Roger Adams in 1940, the structure of CBD was not fully elucidated until 1963. There are four known CBD side chain homologs; methyl, n-propyl, n-butyl, and n-pentyl. CBD does not directly target CB1 and CB2 receptors, does not increase VTA dopamine cell excitation, and has no inherent rewarding properties, but rather affects CB1 receptor transmission by enhancing CB. Although cannabidiol makes up 40% of the plant extract, it does not have the same psychoactive effects as tetrahydrocannabinol.CBD affects endogenous cannabinoid receptors, which are found in the central and peripheral nervous systems. Endogenous cannabinoid receptors are important because they function to maintain homeostasis in the body. Non-psychoactive substances affect endogenous cannabinoid neurotransmitters, which in turn upregulate and downregulate neurotransmission as needed to maintain homeostasis in the body, thus helping to keep the body in a normal and healthy state. In fact, unlike most drugs that only stimulate upregulation or downregulation, CBD is unique in that it balances both. It helps to keep the body in a normal and healthy state. In fact, unlike most drugs that only stimulate upregulation or downregulation, CBD is unique in that it balances both. It helps to keep the body in a normal and healthy state. In fact, unlike most drugs that only stimulate upregulation or downregulation, CBD is unique in that it balances both.
There are many medical claims about CBD and which diseases it is beneficial for?
RR: After thousands of studies, it has been shown to be effective in preventing or treating acne, alcoholism, Alzheimer’s disease, ALS, anxiety, apnea, arthritis, asthma, fractures, all cancers, COPD, depression, diabetes, Dravet syndrome, DTs, eating disorders, endometriosis, epilepsy, fibromyalgia, free radicals, glaucoma, hangovers, heart disease Huntington’s disease, infections, infertility, inflammation, insomnia, liver damage, malaria, migraine, MRSA/CVE infections, nausea, neuropathy, obesity, opiate addiction and withdrawal, organ transplants, pain, pancreatitis, Parkinson’s disease, psychosis, PTSD, rheumatoid arthritis, schizophrenia, sickle cell anemia, stroke, CTE/TBI (concussion), tremor, etc.
SP: Without a doubt, the most prevalent disorders it helps are those such as epilepsy, Parkinson’s, tremors, seizures or most neurological tremor disorders. Because we are witnessing the immediate effects of convulsion cessation and the reduction in the amount of attacks, we do not need more evidence. However, because the plant from which it is derived is still a Schedule 1 substance in the United States, not enough research has been done for it to be officially considered medically beneficial.
AF: CBD is an antibacterial, cancer cell growth inhibitor that protects nerves while promoting bone growth and reducing seizures and convulsions.CBD lowers blood sugar levels, reduces inflammation, lowers the risk of arterial blockage, reduces Sm. intestinal constriction, reduces vomiting and nausea, relieves pain, eases anxiety, slows bacterial growth, inhibits muscle spasms, sedates, treats psoriasis, and vasodilates.
JC: This is a question that we hear a lot. The problem we have with answering this question is that CBD is not a drug, and because the FDA has rules and regulations, we can’t make claims about which diseases it is beneficial for. One thing to point out though is the research done by the U.S. government. pubmed.gov has published hundreds of research articles on their use of CBD to test for different diseases. They have done studies on cancer, epilepsy, anxiety, insomnia, arthritis, nerve damage, etc. Kind of funny when they say cannabis has no positive health benefits but they spend millions studying it? Big Pharma has control over someone ……
AU: CBD has recently been shown to exert tissue-protective effects during chronic myocardial ischemia and reperfusion, and to be cardioprotective. There are indications that CBD may reduce the incidence of arrhythmias and help lower blood pressure – a significant benefit for both hypertensive and Ca imbalanced patients. Recent studies have also shown the great potential of CBD for stroke and sepsis. Recent academic publications describe successful results using CBD as a model for treating pain, multiple sclerosis, inflammation, addiction, depression, and anxiety. on June 25, 2018, the FDA approved the first CBD-based drug (Epidiolex) for the treatment of rare forms of epilepsy (Lennox-Gastaut syndrome and Dravet syndrome ).
CBD is also a rich source of fatty acids and other skin-beneficial nutrients that can be used in infused moisturizers and facial scrubs to address acne, help heal the skin and reduce inflammation so the dermis regenerates faster and stays healthier.
The CBD industry is also beginning to produce products for pets with health conditions similar to those of humans, such as pain, inflammation and anxiety.
What is the current legal status of CBD in the U.S.?
RR: In theory, cannabis grown from a state where it is legal is federally legal if grown under a research program with an agency (or DEA 225 license), which means no cannabis-derived CBD is included.The DEA is permanently banned from enforcing CSA on cannabinoids in cannabis.That said, even states like Colorado that do not comply with the Farm Bill are not affected in any way and therefore do not It was not enforced. For the FDA, it’s a bit sketchy because it hasn’t been considered a pre-existing component of DSHEA, nor has anyone certified it as GRAS or NDI, but again no one has used it in food or oil for hemp seeds. the FDA says it can’t be a dietary supplement because GW has IND products that use CBD, but the FDA is wrong: the use of CBD in products predates GW’s IND application, before DSHEA, before the FDA itself. We have been consuming CBD (best CBD extraction machine online: www.careddi.com/brc/66.htm) for at least 12,000 years.
SP: The U.S. still considers CBD to be a Schedule 1 controlled substance just like THC-9. Currently, we have quite a few federal legalization bills to legalize Hemp, which would allow us to begin building the infrastructure to fully legally grow high CBD low THC-9 cannabis genetics (also known as Hemp), thus creating a for-profit industry in agriculture and manufacturing. The legalization of medical marijuana or hemp is separate, but with our current administration passing the “right to try” bill, I believe it will be legalized and regulated in the pharmaceutical industry by 2021.
AF: The Federal Reserve’s gray market is legal. It will continue at this level unless uniformity and education occur on a large scale nationwide. My concern is that as long as doctors prescribe MJ for “glaucoma”, CBD will be viewed negatively. Honestly, CBD oil can be converted to THC, time and chemicals purchased at The Home Depot mixed together, and if Meth Addicts taught me one thing, there is a way if there is a will – CBD can be converted to THC with sulfuric acid, stress and time.
JC: This is a controversial gray area where some states are pushing for laws around CBD and some states are making laws to make CBD illegal. The Cannabis Association and the DEA Supreme Court ruling basically state that any cannabis product imported into the country and sold to consumers must have a THC content of less than 0.3%. There is currently a 2018 Farm Bill gaining attention and popularity that seeks to remove hemp from the list of controlled substances and enable farmers to once again grow hemp in the United States.
AU: There is widespread confusion as to whether CBD-based products are actually legal. CBD can be produced from hemp or marijuana, so the legality of its production and consumption can be complicated.
A 2014 farm bill legalized “industrial hemp” with a THC content of 0.3 percent or less, contradicting drug laws that still support and prohibit all forms of hemp by the Drug Enforcement Administration. While cannabidiol derived from hemp is federally prohibited, CBD derived from hemp may be legal at the state level and under certain circumstances. As a result, stores advertising low-THC, no-THC CBD, or “cannabis oil” products have begun to develop in many states across the United States, but face resistance from local and federal law enforcement. In addition, according to U.S. Customs and Border Protection, imported cannabis products (including cannabis-derived CBD products) are legal as long as they “do not result in the introduction of THC into the human body and are therefore legal products. However, Domesuc hemp and products made from it are federally prohibited, with some exceptions. CBD products can be made from legally grown domesuc hemp and sold in the states where they are produced. CBD products made from state-legal cannabis plants can also be legal if the products are sold within the state.
The Cole memorandum establishes some protections for this process. the Cole memorandum was originally drafted as a document by former U.S. Oni General James M. Cole in 2013. cole issued a memo to all U.S. Oni through the Department of Justice on August 29, 2013. The memo indicated that prosecutors and law enforcement should focus only on the following priorities related to state-legal marijuana operations.
Preventing the distribution of marijuana to minors
Preventing the flow of proceeds from marijuana sales to criminal enterprises, gangs and cartels.
Preventing the diversion of marijuana in some form from states where it is legal under state law to other states
Preventing state-authorized marijuana activities from being used as a cover or pretext for trafficking in other illegal drugs or other illegal activities.
Preventing the use of violence and the use of firearms in the distribution and circulation of marijuana; preventing the exacerbation of drugged driving and other adverse public health consequences associated with marijuana use
Preventing the growth of marijuana on public lands and the public safety and environmental risks associated with the production of marijuana on public lands.
Preventing the possession or use of marijuana on federal property.